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Associate Scientist Biochemistry & Antigenicity

Meer details
Match criteria
Gewenst aantal uren
  • 32 uur
  • ,
  • Full-time
Dienstverband
  • Tijdelijk
  • ,
  • Vast
Salaris
  • Euro 3200 - 3300
  • ,
  • Obv 40 uur
  • ,
  • Euro 2700 - 2800

Functie omschrijving

The Bacterial Vaccine department is seeking a talented Associate Scientist to join the Biochemical assays and Antigenicity Screening group. The successful candidate will be part of a dynamic and highly motivated team driving the characterization/ and evaluation of large molecule entities that are being developed in different vaccine programms. During your work, you will interact with various Bacterial Vaccines teams, and with Janssen Vaccine support departments. You will be expected to perform laboratory work in person and help contract research organizations (CROs) plan and execute their assignments. This position has therefore a strong focus on biochemical and immunological expertise. Responsibilities include:

  • Chemical modification of bacterial surface molecules;
  • Analysis of antigen-antibody interactions;
  • Analyze carbohydrate, protein-, or glycoconjugate-based antigens;
  • Know, implement and improve established tests for carbohydrates, proteins, glycoconjugates, and particle-based vaccines;
  • Develop new biochemical methods (evaluate LoD, LoQ, accuracy, etc.);
  • With help from product development specialists, design and implement biochemical assays for in-process control (IPC), product characterization, and product release;
  • Support CROs to plan, execute, document, and review their work;

Functie eisen

For this position we are recruiting laboratory professional with the following background:

  • Bachelor or Master degree (BSc / MSc) in a relevant discipline such as (micro) biology, life sciences, biochemistry;
  • 2-4 years of professional experience (industry experience is a must);
  • Expert knowledge on various biochemical assays (large molecules): HPLC, colorimetric assays, ELISA, Cell based assays, labelling of biomolecules;
  • Experience with SPR / Biolayer interferometry / Mesoscale thermophoresis / ITC based screening of biochemical interactions is advantageous;
  • Very good knowledge on bacterial cell surface molecules;
  • Experience and knowledge on chemical modification of microbial surface components;
  • Significant knowledge on purification and enrichment of large biochemical entities;
  • You are a problem solver with a pragmatic hands-on approach;
  • You are a flexible team player who can work well assertively & independently;
  • Valid work permit is a must, PhD is overqualified and will not be taken into consideration.

Bedrijfsprofiel

Janssen Vaccines & Prevention is a leading biotechnology company developing vaccines against infectious diseases. LabResource has been elected as their top supplier for the second year in a row and has been contracted to recruit for this position.

Bedrijfscultuur

The Bacterial Vaccines department focuses on the research and development of vaccines against infectious diseases. Within the Bacterial Vaccines department, the preclinical immunology group evaluates the immunogenicity and efficacy of potential vaccine candidates against infectious diseases in animal models. The main focus of the group is to conduct proof of concept studies and to generate appropriate scientific data that enable our vaccine candidates to progress towards clinical phase evaluation.

Arbeidsvoorwaarden

Contract: 1 year, via LabResource, realistic long term perspectives
Salary: ranging from €2800 - €3400 gross monthly
Hours:full time
Holidays: 25+12
Region: Leiden

Locatie

Leiden

Publicatie datum

15.04.2019

Contactpersoon

T Remijn
T: (020) 4069 750

Meer informatie?
Werk telefoon: (020) 4069 750
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